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Antituberculosis agent-5

Antituberculosis agent-5 (compound 52) is a nitrofuranylamide derivative, inhibits M. tuberculosis UDP-Gal mutase. Antituberculosis agent-5 inhibits Glf activity with an IC50 value of 99 μM/mL and resists tuberculosis (TB) with a MIC value of 1.6 μg/mL[1].

Product Specifications

CAS Number

[313981-44-1]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antituberculosis-agent-5.html

Purity

99.76

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC=C([N+]([O-])=O)O1)NCC2=CC=CC=C2OC

Molecular Formula

C13H12N2O5

Molecular Weight

276.24

Precautions

H315, H319

References & Citations

[1]Tangallapally RP, et al. Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents. J Med Chem. 2004 Oct 7;47 (21) :5276-83.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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