Human Adenylate Kinase 4 (AK 4)

<strong>Human Adenylate Kinase 4 (AK 4)</strong>_x000D_ <strong>Catalog number:</strong> B2015521_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 27.4 kDa (243 aa)_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Adenylate Kinase 4 -Mitochondrial, Adenylate Kinase 3-Like, GTP:AMP phosphotransferase AK4, AK4._x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lalley PA, Francke U, Minna JD. Homologous genes for enolase, phosphogluconate dehydrogenase, phosphoglucomutase, and adenylate kinase are syntenic on mouse chromosome 4 and human chromosome 1p Proc Natl Acad Sci U S A. 1978 May;75(5):2382-6._x000D_ 2: Wujak M, Kozakiewicz A, Ciarkowska A, Loch JI, Barwiolek M, Sokolowska Z, Budny M, Wojtczak A. Assessing the Interactions of Statins with Human Adenylate Kinase Isoenzyme 1: Fluorescence and Enzyme Kinetic Studies Int J Mol Sci. 2021 May 24;22(11):5541._x000D_ 3: Wujak M, Czarnecka J, Gorczycka M, Hetmann A. [Human adenylate kinases - classification, structure, physiological and pathological importance] Postepy Hig Med Dosw (Online). 2015 Jan 2;69:933-45._x000D_ 4: Picher M, Boucher RC. Human airway ecto-adenylate kinase. A mechanism to propagate ATP signaling on airway surfaces J Biol Chem. 2003 Mar 28;278(13):11256-64._x000D_ 5: Liu R, Xu H, Wei Z, Wang Y, Lin Y, Gong W. Crystal structure of human adenylate kinase 4 (L171P) suggests the role of hinge region in protein domain motion Biochem Biophys Res Commun. 2009 Jan 30;379(1):92-7._x000D_ 6: Liu R, Ström AL, Zhai J, Gal J, Bao S, Gong W, Zhu H. Enzymatically inactive adenylate kinase 4 interacts with mitochondrial ADP/ATP translocase Int J Biochem Cell Biol. 2009 Jun;41(6):1371-80._x000D_ 7: Panayiotou C, Solaroli N, Johansson M, Karlsson A. Evidence of an intact N-terminal translocation sequence of human mitochondrial adenylate kinase 4 Int J Biochem Cell Biol. 2010 Jan;42(1):62-9._x000D_ 8: Von Zabern I, Wittmann-Liebold B, Untucht-Grau R, Schirmer RH, Pai EF. Primary and tertiary structure of the principal human adenylate kinase Eur J Biochem. 1976 Sep;68(1):281-90._x000D_ 9: Fujisawa K, Wakazaki M, Matsuzaki A, Matsumoto T, Yamamoto N, Noma T, Takami T. Adenylate Kinase Isozyme 3 Regulates Mitochondrial Energy Metabolism and Knockout Alters HeLa Cell Metabolism Int J Mol Sci. 2022 Apr 13;23(8):4316._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/21556322">10: Dzeja PP, Chung S, Faustino RS, Behfar A, Terzic A. Developmental enhancement of adenylate kinase-AMPK metabolic signaling axis supports stem cell cardiac differentiation PLoS One. 2011 Apr 27;6(4):e19300. </a>_x000D_ _x000D_ <strong>Products Related to Human Adenylate Kinase 4 (AK 4) can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>