SN-38 glucuronide
SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer[1][2][3].
Product Specifications
CAS Number
121080-63-5
Product Name Alternative
SN-38G
UNSPSC
12352005
Hazard Statement
H301, H311, H331
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sn-38-glucuronide.html
Concentration
10mM
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 2.5 mg/mL (ultrasonic; warming; heat to 60°C) |Methanol : 6.25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1OCC2=C(C=C(C3=NC4=CC=C(O[C@H]5[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O5)C=C4C(CC)=C3C6)N6C2=O)[C@@]1(O)CC
Molecular Formula
C28H28N2O11
Molecular Weight
568.53
Precautions
H301, H311, H331
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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