Mcl1-IN-1
Mcl1-IN-1 is an inhibitor of myeloid cell factor 1 (Mcl-1) (IC50=2.4 μM) .
Product Specifications
CAS Number
[713492-66-1]
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Mcl1-IN-1.html
Purity
98.02
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(O)COC1=CC=CC=C1C(NC2=NC=CC=C2)C3=C(O)C4=NC=CC=C4C(Cl)=C3
Molecular Formula
C23H18ClN3O4
Molecular Weight
435.86
References & Citations
[1]Richard DJ, et al. Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker. Bioorg Med Chem. 2013 Nov 1;21 (21) :6642-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Mcl-1
Available Sizes
Curated Selection
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