R406 (free base)

841290-80-0

6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one

Tyrosine Kinase Spleen Tyrosine Kinase (Syk)

0.98

A solid

≥23.5 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O

CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C

C22H23FN6O5

470.4

Blue ice

Store at -20°C.