AEE788 (NVP-AEE788)

497839-62-0

6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

JAK STAT Signaling EGFR Tyrosine Kinase EGFR

0.98

A solid

≥22.05 mg/mL in DMSO; insoluble in H2O; ≥14.4 mg/mL in EtOH with ultrasonic

CCN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(N3)N=CN=C4NC(C)C5=CC=CC=C5

C27H32N6

440.58

Blue ice

Store at -20°C.