Neuromedin U, rat (TFA)

Neuromedin U, rat TFA is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy balance, stress response, and nociception.

Product Specifications

Product Name Alternative

Neuromedin U (rat) (TFA) ; Rat neuromedin U-23 (TFA)

UNSPSC

12352209

Target

Neuromedin U Receptor (NMUR)

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/neuromedin-u-rat-tfa.html

Purity

99.90

Solubility

DMSO : 25 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

OC(C(F)(F)F)=O.O=C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(O)=O)C(NCC(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H](CO)C(NCC(NCC(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC(C)C)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CCCNC(N)=N)C(N6[C@@H](CCC6)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC7=CC=C(C=C7)O)N

Molecular Formula

C126H181N34F3O33

Molecular Weight

2756.99

References & Citations

[1]Liu JJ, et al. Discovery and pharmacological characterization of a small-molecule antagonist at neuromedin U receptor NMUR2. J Pharmacol Exp Ther. 2009 Jul;330 (1) :268-75.