(S, R, S) -AHPC-PEG4-acid
(S, R, S) -AHPC-PEG4-acid is a synthetic PROTAC ligand that binds the E3 ligase ligand to the PEG4 arm, thereby enhancing PROTAC drug research and discovery[1].
Product Specifications
CAS Number
[2172820-12-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-peg4-acid.html
Purity
98.26
Solubility
10 mM in DMSO
Smiles
OC(CCOCCOCCOCCOCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O)=O
Molecular Formula
C34H50N4O10S
Molecular Weight
706.85
Precautions
H302, H315, H319, H335
References & Citations
[1]Jian Jin, et al. Compositions and methods for treating ezh2-mediated cancer. WO2018081530A1.2018-05-03.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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