Amuvatinib (MP-470, HPK 56)

850879-09-3

N-(1,3-benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide

MP470,MP 470,HPK56

Tyrosine Kinase c-Kit Apoptosis c-RET Tyrosine Kinase c-RET Tyrosine Kinase FLT3 Tyrosine Kinase PDGFR

0.9991

A solid

≥22.4 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH

C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6

C23H21N5O3S

447.51

Blue ice

Store at -20°C.