MK-5108 (VX-689)

1010085-13-8

4-(3-chloro-2-fluorophenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid

Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase

0.9691

A solid

≥23.1 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O

C1CC(CCC1OC2=C(C(=CC=C2)Cl)F)(CC3=NC(=CC=C3)NC4=NC=CS4)C(=O)O

C22H21ClFN3O3S

461.94

Blue ice

Store at -20°C.