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MK-5108 (VX-689)

Aurora-A kinase inhibitor,highly selective

Product Specifications

CAS Number

1010085-13-8

Product Name Alternative

4-(3-chloro-2-fluorophenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid

Field of Research

Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase

Purity

0.9691

Form

A solid

Solubility

≥23.1 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O

Smiles

C1CC(CCC1OC2=C(C(=CC=C2)Cl)F)(CC3=NC(=CC=C3)NC4=NC=CS4)C(=O)O

Molecular Formula

C22H21ClFN3O3S

Molecular Weight

461.94

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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