Danusertib (PHA-739358)
Pan-aurora kinase inhibitor
Product Specifications
Product Name Alternative
N-[5-[(2R)-2-methoxy-2-phenylacetyl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
Sequence
5-Amido-pyrrolopyrazole 9d
Field of Research
Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase Apoptosis c-RET Tyrosine Kinase c-RET Tyrosine Kinase FGFR
Purity
0.9939
Form
A solid
Solubility
≥23.75 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
Smiles
CN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3=NNC4=C3CN(C4)C(=O)C(C5=CC=CC=C5)OC
Molecular Formula
C26H30N6O3
Molecular Weight
474.55
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
CAS Number
827318-97-8
Curated Selection
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