Danusertib (PHA-739358)

827318-97-8

N-[5-[(2R)-2-methoxy-2-phenylacetyl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide

5-Amido-pyrrolopyrazole 9d

Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase Apoptosis c-RET Tyrosine Kinase c-RET Tyrosine Kinase FGFR

0.9939

A solid

≥23.75 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O

CN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3=NNC4=C3CN(C4)C(=O)C(C5=CC=CC=C5)OC

C26H30N6O3

474.55

Blue ice

Store at -20°C.