VX-680 (MK-0457,Tozasertib)
Aurora kinase inhibitor
Product Specifications
CAS Number
639089-54-6
Product Name Alternative
N-[4-[4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]sulfanylphenyl]cyclopropanecarboxamide
Field of Research
Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase
Purity
0.9993
Form
A solid
Solubility
≥23.25 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
Smiles
CC1=CC(=NN1)NC2=NC(=NC(=C2)N3CCN(CC3)C)SC4=CC=C(C=C4)NC(=O)C5CC5
Molecular Formula
C23H28N8OS
Molecular Weight
464.59
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
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