MLN8237 (Alisertib)

1028486-01-2

4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxybenzoic acid

Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase

0.9877

A solid

≥25.95 mg/mL in DMSO; insoluble in H2O; insoluble in ETOH

COC1=C(C(=CC=C1)F)C2=NCC3=CN=C(N=C3C4=C2C=C(C=C4)Cl)NC5=CC(=C(C=C5)C(=O)O)OC

C27H20ClFN4O4

518.92

Blue ice

Store at -20°C.