Glycopyrrolate

Glycopyrrolate (Glycopyrronium bromide), a quaternary ammonium derivative, is a muscarinic receptor antagonist. Glycopyrrolate has bronchoprotective effect and produces a beneficial effect on blood pressure. Glycopyrrolate can be used for the research of bronchial diseases[1][2][3].

Product Specifications

CAS Number

[596-51-0]

Product Name Alternative

Glycopyrronium (bromide) ; Glycopyrrolate (bromide)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Glycopyrrolate.html

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

C[N+]1(C)CC(OC(C(O)(C2CCCC2)C3=CC=CC=C3)=O)CC1.[Br-]

Molecular Formula

C19H28BrNO3

Molecular Weight

398.33

Precautions

H302, H315, H319, H335

References & Citations

[1]Maarsingh H, et al. Effects of (a Combination of) the Beta2-Adrenoceptor Agonist Indacaterol and the Muscarinic Receptor Antagonist Glycopyrrolate on Intrapulmonary Airway Constriction [J]. Cells, 2021, 10 (5) : 1237.|[2]Dyson D H, et al. Dose effect and benefits of glycopyrrolate in the treatment of bradycardia in anesthetized dogs [J]. The Canadian Veterinary Journal, 1999, 40 (5) : 327.|[3]Hansel T T, Neighbour H, Erin E M, et al. Glycopyrrolate causes prolonged bronchoprotection and bronchodilatation in patients with asthma [J]. Chest, 2005, 128 (4) : 1974-1979.