XL228

898280-07-4

4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine

XL-228;XL 228

Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase Tyrosine Kinase Src

0.9932

A solid

≥21.9 mg/mL in DMSO; insoluble in H2O; ≥27.6 mg/mL in EtOH with gentle warming and ultrasonic

CC(C)C1=NOC(=C1)CNC2=NC(=CC(=N2)NC3=NNC(=C3)C4CC4)N5CCN(CC5)C

C22H31N9O

437.54

Blue ice

Store at -20°C.