XL228
IGF1R/AURORA /FGFR1-3/ABL/SRC family kinases inhibitor
Product Specifications
Product Name Alternative
4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine
Sequence
XL-228;XL 228
Field of Research
Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase Tyrosine Kinase Src
Purity
0.9932
Form
A solid
Solubility
≥21.9 mg/mL in DMSO; insoluble in H2O; ≥27.6 mg/mL in EtOH with gentle warming and ultrasonic
Smiles
CC(C)C1=NOC(=C1)CNC2=NC(=CC(=N2)NC3=NNC(=C3)C4CC4)N5CCN(CC5)C
Molecular Formula
C22H31N9O
Molecular Weight
437.54
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
CAS Number
898280-07-4
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