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RG7388

MDM2 antagonist, oral, selective

Product Specifications

Product Name Alternative

4-[[(2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]-3-methoxybenzoic acid

Sequence

RG 7388;RG-7388

Field of Research

Apoptosis MDM2 Apoptosis p53

Purity

0.9982

Form

A solid

Solubility

≥30.82 mg/mL in DMSO; insoluble in H2O; ≥6.96 mg/mL in EtOH with gentle warming

Smiles

CC(C)(C)CC1C(C(C(N1)C(=O)NC2=C(C=C(C=C2)C(=O)O)OC)C3=C(C(=CC=C3)Cl)F)(C#N)C4=C(C=C(C=C4)Cl)F

Molecular Formula

C31H29Cl2F2N3O4

Molecular Weight

616.48

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

CAS Number

1229705-06-9

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