RG7112
MDM2 inhibitor, first clinical
Product Specifications
CAS Number
939981-39-2
Product Name Alternative
[(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethylimidazol-1-yl]-[4-(3-methylsulfonylpropyl)piperazin-1-yl]methanone
Sequence
RG-7112;RG 7112
Field of Research
Apoptosis MDM2 Apoptosis p53
Purity
0.9858
Form
A solid
Solubility
≥36.4 mg/mL in DMSO; insoluble in H2O; ≥31.87 mg/mL in EtOH
Smiles
CCOC1=C(C=CC(=C1)C(C)(C)C)C2=NC(C(N2C(=O)N3CCN(CC3)CCCS(=O)(=O)C)(C)C4=CC=C(C=C4)Cl)(C)C5=CC=C(C=C5)Cl
Molecular Formula
C38H48Cl2N4O4S
Molecular Weight
727.78
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
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