RG7112

939981-39-2

[(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethylimidazol-1-yl]-[4-(3-methylsulfonylpropyl)piperazin-1-yl]methanone

RG-7112;RG 7112

Apoptosis MDM2 Apoptosis p53

0.9858

A solid

≥36.4 mg/mL in DMSO; insoluble in H2O; ≥31.87 mg/mL in EtOH

CCOC1=C(C=CC(=C1)C(C)(C)C)C2=NC(C(N2C(=O)N3CCN(CC3)CCCS(=O)(=O)C)(C)C4=CC=C(C=C4)Cl)(C)C5=CC=C(C=C5)Cl

C38H48Cl2N4O4S

727.78

Blue ice

Store at -20°C.