Regorafenib monohydrate

1019206-88-2

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide;hydrate

BAY 73-4506 monohydrate

Apoptosis c-RET Tyrosine Kinase c-RET Tyrosine Kinase VEGFR

0.9931

A solid

≥25.05 mg/mL in DMSO; insoluble in H2O

CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F.O

C21H17ClF4N4O4

500.83

Blue ice

Store at -20°C.