Regorafenib hydrochloride

835621-07-3

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide hydrochloride

BAY73-4506 hydrochloride

Apoptosis c-RET Tyrosine Kinase c-RET Tyrosine Kinase VEGFR

0.9857

A solid

≥25.95 mg/mL in DMSO; insoluble in H2O; ≥8.75 mg/mL in EtOH with gentle warming and ultrasonic

CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F.Cl

C21H16Cl2F4N4O3

519.28

Blue ice

Store at -20°C.