LY2835219 free base

1231929-97-7

N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine

CDK4/6 dual inhibitor;LY 2835219 (free base);LY-2835219 (free base)

Cell Cycle Checkpoint Cyclin-Dependent Kinases

0.9942

A solid

insoluble in H2O; ≥4.83 mg/mL in DMSO with gentle warming and ultrasonic; ≥6.34 mg/mL in EtOH with gentle warming

CCN1CCN(CC2=CN=C(NC3=NC=C(F)C(C4=CC5=C(N=C(C)N5C(C)C)C(F)=C4)=N3)C=C2)CC1

C27H32F2N8

506.59

Blue ice

Store at -20°C.