Dabrafenib Mesylate (GSK-2118436)
Inhibitor of BRAF(V600) mutants
Product Specifications
CAS Number
1195768-06-9
Product Name Alternative
N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide;methanesulfonic acid
Sequence
GSK-2118436 Mesylate;GSK2118436 Mesylate;GSK 2118436 Mesylate;GSK 2118436B,Tafinlar,
Field of Research
MAPK Signaling Raf
Purity
0.9978
Form
A solid
Solubility
≥30.75 mg/mL in DMSO; insoluble in H2O; ≥2.74 mg/mL in EtOH with gentle warming and ultrasonic
Smiles
CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F.CS(=O)(=O)O
Molecular Formula
C24H24F3N5O5S3
Molecular Weight
615.67
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
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