Dabrafenib Mesylate (GSK-2118436)

1195768-06-9

N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide;methanesulfonic acid

GSK-2118436 Mesylate;GSK2118436 Mesylate;GSK 2118436 Mesylate;GSK 2118436B,Tafinlar,

MAPK Signaling Raf

0.9978

A solid

≥30.75 mg/mL in DMSO; insoluble in H2O; ≥2.74 mg/mL in EtOH with gentle warming and ultrasonic

CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F.CS(=O)(=O)O

C24H24F3N5O5S3

615.67

Blue ice

Store at -20°C.