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CO-1686 (AVL-301)

EGFR inhibitor

Product Specifications

CAS Number

1374640-70-6

Product Name Alternative

N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxyanilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Sequence

AVL-301;CNX-419; Rociletinib

Field of Research

JAK STAT Signaling EGFR Tyrosine Kinase EGFR

Purity

0.9928

Form

A solid

Solubility

≥27.8 mg/mL in DMSO; insoluble in H2O; ≥4.68 mg/mL in EtOH with gentle warming and ultrasonic

Smiles

CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)C(F)(F)F)OC

Molecular Formula

C27H28F3N7O3

Molecular Weight

555.55

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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