Canertinib dihydrochloride

289499-45-2

N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide;dihydrochloride

PD-183805; CI-1033;Canertinib HCl;PD183805; CI103;PD 183805; CI 103

Tyrosine Kinase HER2

0.9972

A solid

≥21.8 mg/mL in H2O with gentle warming and ultrasonic; ≥55.9 mg/mL in DMSO with gentle warming; ≥8.96 mg/mL in EtOH with gentle warming and ultrasonic

C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4.Cl.Cl

C24H27Cl3FN5O3

558.87

Blue ice

Store at -20°C.