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AST 487

RET kinase inhibitor

Product Specifications

Product Name Alternative

1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea

Sequence

NVP-AST 487

Field of Research

Tyrosine Kinase FLT3

Purity

0.9929

Solubility

≥26.5 mg/mL in DMSO; insoluble in H2O; ≥51.2 mg/mL in EtOH

Smiles

CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)NC3=CC=C(C=C3)OC4=NC=NC(=C4)NC)C(F)(F)F

Molecular Formula

C26H30F3N7O2

Molecular Weight

529.56

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

CAS Number

630124-46-8

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