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Afatinib dimaleate

EGFR inhibitor

Product Specifications

Product Name Alternative

(Z)-but-2-enedioic acid;(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Sequence

BIBW 2992MA2; BIBW-2992; BIBW2992; BIBW 2992; Afatinib

Field of Research

Tyrosine Kinase HER2

Purity

0.9828

Form

A solid

Solubility

≥35.9 mg/mL in DMSO; ≥147.2 mg/mL in H2O; ≥6.39 mg/mL in EtOH with gentle warming and ultrasonic

Smiles

CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O

Molecular Formula

C32H33ClFN5O11

Molecular Weight

718.08

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

CAS Number

850140-73-7

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