(R)-Crizotinib

877399-52-5

3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine

Crizotinib,PF-2341066, PF02341066, PF 2341066

Tyrosine Kinase ALK Tyrosine Kinase c-MET

0.9932

A solid

insoluble in H2O; insoluble in EtOH; ≥7.51 mg/mL in DMSO

CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N

C21H22Cl2FN5O

450.34

Blue ice

Store at -20°C.