Trametinib (GSK1120212)

MEK1 and MEK2 inhibitor, potent and selective

Product Specifications

CAS Number

871700-17-3

Product Name Alternative

N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide

Sequence

Trametinib, GSK-1120212, GSK1120212, Mekinist, JTP74057, JTP-74057

Field of Research

MAPK Signaling MEK1 2

Purity

0.9814

Form

A solid

Solubility

insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL in DMSO

Smiles

CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC(=CC=C4)NC(=O)C)C5CC5

Molecular Formula

C26H23FIN5O4

Molecular Weight

615.39

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-22590IR 0.1 mL

Mouse Monoclonal KRT23 Antibody (2F6) [DyLight 755]

Ask

View Details

GTR15081561 1 Vial

Lentiviral human TRAFD1 shRNA (UAS) - Lentiviral human TRAFD1 shRNA (UAS, GFP) (100)

Ask

View Details

134960-ML550 100 µL

Tyrosinase (TYR, LB24 AB, LB24-AB, Monophenol Monooxygenase, Oculocutaneous Albinism IA, OCA1A, OCAIA, SK29 AB, SK29-AB, Tumor Rejection Antigen AB) (MaxLight 550)

Ask

View Details

MBS7101532 Inquire

Recombinant Vibrio harveyi Na (+)-translocating NADH-quinone reductase subunit C (nqrC), partial

Ask

View Details

bs-4587R-BF350-01 20 µL

IL-6 Polyclonal Antibody, AbBy Fluor™ 350 Conjugated

Ask

View Details

bs-4587R-BF350-02 100 µL

IL-6 Polyclonal Antibody, AbBy Fluor™ 350 Conjugated

Ask

View Details