Trametinib (GSK1120212)
MEK1 and MEK2 inhibitor, potent and selective
Product Specifications
CAS Number
871700-17-3
Product Name Alternative
N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide
Sequence
Trametinib, GSK-1120212, GSK1120212, Mekinist, JTP74057, JTP-74057
Field of Research
MAPK Signaling MEK1 2
Purity
0.9814
Form
A solid
Solubility
insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL in DMSO
Smiles
CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC(=CC=C4)NC(=O)C)C5CC5
Molecular Formula
C26H23FIN5O4
Molecular Weight
615.39
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
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