CHIR-99021 (CT99021)

252917-06-9

6-((2-((4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile

CHIR99021, CHIR-99021, CHIR 99021, CT99021,GSK-3 Inhibitor XVI

PI3K Akt mTOR Signaling GSK-3 Stem Cell GSK-3 Stem Cell iPSC Stem Cell Wnt β-catenin

0.9592

A solid

≥23.27 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH

N#CC1=CC=C(NCCNC2=NC=C(C3=NC=C(C)N3)C(C4=CC=C(Cl)C=C4Cl)=N2)N=C1

C22H18Cl2N8

465.34

Blue ice

Store at -20°C.