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GDC-0068 (RG7440)

Pan-AKT inhibitor,highly selective

Product Specifications

CAS Number

1001264-89-6

Product Name Alternative

(2S)-2-(4-chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-ylamino)propan-1-one

Sequence

GDC0068,RG7440,CS0975

Field of Research

PI3K Akt mTOR Signaling Akt

Purity

0.9906

Form

A solid

Solubility

≥22.9 mg/mL in DMSO; insoluble in H2O; ≥28.35 mg/mL in EtOH

Smiles

CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O

Molecular Formula

C24H32ClN5O2

Molecular Weight

458

Shipping Conditions

Blue ice

Storage Conditions

Desiccate at -20°C.

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