GDC-0068 (RG7440)

1001264-89-6

(2S)-2-(4-chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-ylamino)propan-1-one

GDC0068,RG7440,CS0975

PI3K Akt mTOR Signaling Akt

0.9906

A solid

≥22.9 mg/mL in DMSO; insoluble in H2O; ≥28.35 mg/mL in EtOH

CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O

C24H32ClN5O2

458

Blue ice

Desiccate at -20°C.