GDC-0068 (RG7440)
Pan-AKT inhibitor,highly selective
Product Specifications
CAS Number
1001264-89-6
Product Name Alternative
(2S)-2-(4-chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-ylamino)propan-1-one
Sequence
GDC0068,RG7440,CS0975
Field of Research
PI3K Akt mTOR Signaling Akt
Purity
0.9906
Form
A solid
Solubility
≥22.9 mg/mL in DMSO; insoluble in H2O; ≥28.35 mg/mL in EtOH
Smiles
CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O
Molecular Formula
C24H32ClN5O2
Molecular Weight
458
Shipping Conditions
Blue ice
Storage Conditions
Desiccate at -20°C.
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