Vemurafenib (PLX4032, RG7204)
BRAF kinase inhibitor
Product Specifications
CAS Number
918504-65-1
Product Name Alternative
N-[3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]propane-1-sulfonamide
Sequence
Vemurafenib, Zelboraf, PLX-4032, RG7204, RO5185426
Field of Research
MAPK Signaling MEK1 2 MAPK Signaling Raf
Purity
0.9848
Form
A solid
Solubility
≥24.5 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
Smiles
CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)C4=CC=C(C=C4)Cl)F
Molecular Formula
C23H18ClF2N3O3S
Molecular Weight
489.93
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
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