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VX-661

F508del CFTR corrector

Product Specifications

Product Name Alternative

1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide

Field of Research

Membrane Transporter Ion Channel CFTR

Purity

0.9988

Form

A solid

Solubility

≥21.8 mg/mL in DMSO; insoluble in EtOH; ≥24.3 mg/mL in H2O

Smiles

CC(C)(CO)C1=CC2=CC(=C(C=C2N1CC(CO)O)F)NC(=O)C3(CC3)C4=CC5=C(C=C4)OC(O5)(F)F

Molecular Formula

C26H27F3N2O6

Molecular Weight

520.5

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

CAS Number

1152311-62-0

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