Celastrol

34157-83-0

(2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid

Immunology Inflammation IκB IKK Ubiquitination Proteasome Proteasome Apoptosis TNF-α

0.9975

A solid

≥22.55 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH

O=C1C(O)=C(C)C2=CC=C([C@](CC[C@]3(C)[C@@]4([H])C[C@@](C(O)=O)(C)CC3)(C)[C@@]4(C)CC5)[C@]5(C)C2=C1

C29H38O4

450.61

Blue ice

Store at -20°C.