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Carfilzomib (PR-171)

Proteasome inhibitor, epoxomicin analog

Product Specifications

CAS Number

868540-17-4

Product Name Alternative

(2S)-4-methyl-N-[(2S)-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]-4-phenylbutanoyl]amino]pentanamide

Sequence

PR 171, PR171, PR-171, Carfilzomib

Field of Research

Ubiquitination Proteasome Proteasome

Purity

0.9976

Form

A solid

Solubility

≥35.99 mg/mL in DMSO; insoluble in H2O; ≥2.64 mg/mL in EtOH with gentle warming and ultrasonic

Smiles

CC(C)CC(C(=O)C1(CO1)C)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(CCC3=CC=CC=C3)NC(=O)CN4CCOCC4

Molecular Formula

C40H57N5O7

Molecular Weight

719.91

Shipping Conditions

Blue ice

Storage Conditions

Desiccate at -20°C.

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