Carfilzomib (PR-171)
Proteasome inhibitor, epoxomicin analog
Product Specifications
CAS Number
868540-17-4
Product Name Alternative
(2S)-4-methyl-N-[(2S)-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]-4-phenylbutanoyl]amino]pentanamide
Sequence
PR 171, PR171, PR-171, Carfilzomib
Field of Research
Ubiquitination Proteasome Proteasome
Purity
0.9976
Form
A solid
Solubility
≥35.99 mg/mL in DMSO; insoluble in H2O; ≥2.64 mg/mL in EtOH with gentle warming and ultrasonic
Smiles
CC(C)CC(C(=O)C1(CO1)C)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(CCC3=CC=CC=C3)NC(=O)CN4CCOCC4
Molecular Formula
C40H57N5O7
Molecular Weight
719.91
Shipping Conditions
Blue ice
Storage Conditions
Desiccate at -20°C.
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