GPI-1485
GPI-1485 (GM1485), a nonimmunosuppressive immunophilin ligand, promotes neurofunctional improvement and neural regeneration following stroke[1].
Product Specifications
CAS Number
[186268-78-0]
Product Name Alternative
GM1485
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
FKBP
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gpi-1485.html
Purity
99.56
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)[C@H]1N(C(C(C(C)(C)CC)=O)=O)CCC1
Molecular Formula
C12H19NO4
Molecular Weight
241.28
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
References & Citations
[1]Andrew F Ducruet , et al. GM1485, a Nonimmunosuppressive Immunophilin Ligand, Promotes Neurofunctional Improvement and Neural Regeneration Following Stroke. J Neurosci Res. 2012 Jul;90 (7) :1413-23.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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