Canertinib (CI-1033)

267243-28-7

N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide

JAK STAT Signaling EGFR Tyrosine Kinase EGFR

0.9952

A solid

insoluble in H2O; ≥10.1 mg/mL in EtOH; ≥12.15 mg/mL in DMSO with gentle warming

C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4

C24H25ClFN5O3

485.94

Blue ice

Store at -20°C.