Pelitinib (EKB-569)

257933-82-7

(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide

JAK STAT Signaling EGFR Tyrosine Kinase EGFR Tyrosine Kinase HER2

0.9849

A solid

insoluble in EtOH; insoluble in H2O; ≥11.7 mg/mL in DMSO

CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)F)Cl)C#N)NC(=O)C=CCN(C)C

C24H23ClFN5O2

467.92

Blue ice

Store at -20°C.