Duvelisib (IPI-145, INK1197)

1201438-56-3

(S)-3-(1-((9H-purin-6-yl)amino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one

PI3K Akt mTOR Signaling PI3K

0.9955

A solid

≥20.84 mg/mL in DMSO; insoluble in H2O; ≥24.9 mg/mL in EtOH

O=C1N(C([C@H](C)NC2=C3N=CNC3=NC=N2)=CC4=C1C(Cl)=CC=C4)C5=CC=CC=C5

C22H17ClN6O

416.86

Blue ice

Store at -20°C.