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WZ4002

Mutant-selective EGFR inhibitor(L858R,T790M), irreversible and potent

Product Specifications

Product Name Alternative

N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Field of Research

JAK STAT Signaling EGFR Tyrosine Kinase EGFR

Purity

0.9889

Form

A solid

Solubility

≥24.7 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH

Smiles

CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC(=C4)NC(=O)C=C)Cl)OC

Molecular Formula

C25H27ClN6O3

Molecular Weight

494.18

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

CAS Number

1213269-23-8

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