ALK-IN-1

1197958-12-5

5-chloro-2-N-[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl]-4-N-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine

Brigatinib analog

Tyrosine Kinase ALK JAK STAT Signaling EGFR Tyrosine Kinase EGFR Tyrosine Kinase FGFR

0.98

A solid

≥26.45 mg/mL in DMSO; insoluble in H2O; ≥55.9 mg/mL in EtOH

CN(C)C1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=CC=C4P(=O)(C)C)Cl)OC

C26H34ClN6O2P

529.01

Blue ice

Store at -20°C.