Tyk2-IN-15
Tyk2-in-15 (Compound 97) is a selective tyrosine kinase 2 (Tyk2) inhibitor with IC50 value ≤ 10 nM for Tyk2-JH2. Tyk2-IN-15 can be used in the study of inflammatory or autoimmune diseases[1].
Product Specifications
CAS Number
[3010873-44-3]
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tyk2-in-15.html
Solubility
10 mM in DMSO
Smiles
CC(NC1=NC=C2C(N3C[C@H](CC3)N(C)C)=NN(C4=CC=CC(C(F)(F)C)=N4)C2=C1)=O
Molecular Formula
C21H25F2N7O
Molecular Weight
429.47
References & Citations
[1]TeYu CHEN, et al. Tyk2 inhibitors. WO2023220046A1. 2023-11-16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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