Tyk2-IN-15

Tyk2-in-15 (Compound 97) is a selective tyrosine kinase 2 (Tyk2) inhibitor with IC50 value ≤ 10 nM for Tyk2-JH2. Tyk2-IN-15 can be used in the study of inflammatory or autoimmune diseases[1].

Product Specifications

CAS Number

[3010873-44-3]

UNSPSC

12352005

Target

JAK

Type

Reference compound

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tyk2-in-15.html

Solubility

10 mM in DMSO

Smiles

CC(NC1=NC=C2C(N3C[C@H](CC3)N(C)C)=NN(C4=CC=CC(C(F)(F)C)=N4)C2=C1)=O

Molecular Formula

C21H25F2N7O

Molecular Weight

429.47

References & Citations

[1]TeYu CHEN, et al. Tyk2 inhibitors. WO2023220046A1. 2023-11-16.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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