Cysteamine-d4 (hydrochloride)

Cysteamine-d4 (hydrochloride) is the deuterium labeled Cysteamine hydrochloride. Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.

Product Specifications

CAS Number

[1219805-04-5]

Product Name Alternative

2-Aminoethanethiol-d4 (hydrochloride) ; 2-Mercaptoethylamine-d4 (hydrochloride)

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Metabolic Disease; Cancer

Purity

99.77

Solubility

10 mM in DMSO

Smiles

SC([2H])([2H])C([2H])([2H])N.Cl

Molecular Formula

C2H4D4ClNS

Molecular Weight

117.63

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Besouw, M., et al., Cysteamine: an old drug with new potential. Drug Discov Today, 2013. 18 (15-16) : p. 785-92.|[3]de Matos, D.G., et al., Effect of cysteamine on glutathione level and developmental capacity of bovine oocyte matured in vitro. Mol Reprod Dev, 1995. 42 (4) : p. 432-6.